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Friday, February 03, 2012 | Source: European Heart Journal

Study Focuses on Systemic Inflammation After TAVR

By Caitlin E. Cox

Systemic inflammation occurs in a substantial proportion of patients after transcatheter aortic valve replacement (TAVR), according to a paper published…

Friday, February 03, 2012 | Source: Society of Thoracic Surgeons

ASCERT: Long-term Survival Appears to Favor CABG Over PCI for Multivessel Disease

By L.A. McKeown

Among ‘real world’ patients with multivessel disease, percutaneous coronary intervention (PCI) improves survival compared with coronary artery bypass…

Thursday, February 02, 2012 | Source: Society of Thoracic Surgeons

PARTNER: TAVR Compares Well Even With Minimally Invasive Surgery

By Jason Kahn

While cohort A of the PARTNER trial established transcatheter aortic valve replacement (TAVR) as noninferior to surgical AVR for high risk patients…

Thursday, February 02, 2012 | Source: Journal of the American College of Cardiology

Expert Consensus Document on TAVR Provides ‘Roadmap’ for Clinicians

By Yael L. Maxwell

On the heels of the United States Food and Drug Administration’s (FDA) November 2011 approval of the first prosthetic device for use in transcatheter…

Wednesday, February 01, 2012 | Source: Journal of the American College of Cardiology

New Revascularization Appropriateness Criteria Feature PCI Upgrades

By Kim Dalton

Drawing on 2 years’ worth of new data, an expert task force has published updated appropriate use criteria for revascularization. The new guidelines,…

Wednesday, February 01, 2012 | Source: New England Journal of Medicine

CREST Analysis: Restenosis Rates Similar at 2 Years for Carotid Stenting, Surgery

By Caitlin E. Cox

Carotid endarterectomy (CEA) and carotid artery stenting (CAS) produce equivalent levels of restenosis out to 2 years following intervention, according…

Tuesday, January 31, 2012 | Source: Archives of Internal Medicine

Iodinated Contrast Agents Tied to Potential Thyroid Dysfunction

By Yael L. Maxwell

Iodinated contrast media exposure is associated with development of hyperthyroidism as well as overt hypothyroidism, according to results from a study…

Tuesday, January 31, 2012 | Source: Circulation

PCI with Concomitant Aortic Stenosis May Not Increase Short-term Mortality

By L.A. McKeown

The presence of severe symptomatic aortic stenosis has little impact on rates of short term mortality and procedural complications in patients undergoing…

Monday, January 30, 2012 | Source: Conference on Cell Therapy for Cardiovascular Disease

Expedited Cell Therapy After STEMI Shows Promise

By Kim Dalton

NEW YORK, NY—Data from a pair of small, preliminary studies suggest that stem cell therapy is safe and may improve long term cardiac function in patients…

Monday, January 30, 2012 | Source: Journal of the American College of Cardiology

Women Benefit From TAVR as Much as Men, Maybe More

By Jason Kahn

Despite different baseline and anatomical characteristics, women with severe aortic stenosis show equivalent short term benefits from transcatheter…

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Monday, September 26, 2011 | Source: Clinical TrialsCardiosource

Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Myocardial Infarction

By Clinical Trials

The goal of the trial was to evaluate pretreatment with clopidogrel 600 mg compared with 300 mg among patients with ST-segment elevation myocardial…

Friday, September 09, 2011 | Source: Journal ScansCardiosource

Prognostic Significance of Coronary Thrombus in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes: A Subanalysis of the ACUITY (Acute Catheterization and Urgent In...

By Journal Scans

Coronary thrombus was seen in 15% of the patients. Preprocedural thienopyridines and glycoprotein (GP) IIb/IIIa inhibitors were associated with a…

Tuesday, August 30, 2011 | Source: Clinical TrialsCardiosource

Safety, Tolerability, and Efficacy of Darexaban (YM150) in Patients With Acute Coronary Syndrome

By Clinical Trials

Darexaban is a novel oral factor Xa inhibitor, and has been shown to be effective in the treatment of venous thromboembolism (VTE). The current…

Tuesday, August 30, 2011 | Source: Clinical TrialsCardiosource

A clinical Evaluation of Xience V stent in Acute Myocardial INfArcTION

By Clinical Trials

Numerous studies have documented the safety and efficacy of drug-eluting stent (DES) use over bare-metal stent (BMS) use in patients presenting…

Tuesday, August 30, 2011 | Source: Clinical TrialsCardiosource

Counterpulsation to Reduce Infarct Size Pre-PCI Acute Myocardial Infarction

By Clinical Trials

Patients presenting with anterior ST-segment elevation myocardial infarction (STEMI) are at high risk for adverse outcomes, despite undergoing primary…

Thursday, July 28, 2011 | Source: CardiosourceCardiosource

Aspirin for the Prevention of CV Events in Patients Without Clinical CV Disease

By Journal Scans

Over a mean follow-up of 6.9 years, aspirin was associated with a reduction in MCEs (risk ratio [RR], 0.90; 95% confidence interval [CI], 0.85-0.96;…

Wednesday, July 27, 2011 | Source: CardiosourceCardiosource

RF Ablation of A-Fib in Patients With Mitral or Aortic Mechanical Prosthetic Valves

By Journal Scans

The mean international normalized ratio during the procedure was 2.8 in the prosthetic valve group. The mean procedure time (199 vs. 167 minutes) and…

Thursday, July 21, 2011 | Source: CardiosourceCardiosource

Race, Ethnicity, and the Efficacy of Rosuvastatin in Primary Prevention: The JUPITER Trial

By ACC Journal Scans

There was no difference at baseline for the following: median age 66 years, body mass index, or history of hypertension. Nonwhites were more often…

Thursday, July 21, 2011 | Source: CardiosourceCardiosource

Diagnostic Accuracy of Dual-Source Multislice CT in 100 Patients With Tetralogy of Fallot

By ACC Journal Scans

The median age at repair was 6.8 months (range 1.2 months to 6.8 years). Coronary artery abnormalities were noted in seven (7%) patients. Compared…

Wednesday, July 20, 2011 | Source: CardiosourceCardiosource

Carotid-Wall Intima–Media Thickness and Cardiovascular Events

By ACC Journal Scans

A total of 296 participants had a cardiovascular event. The risk factors of the Framingham risk score predicted these events, with a c-statistic of…

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Friday, December 02, 2011 | Source: TCT 2011

Adenosine-Free Pressure Measurement Found Equivalent to FFR

By L.A. McKeown

SAN FRANCISCO, CA—A new type of intracoronary resistance measurement that takes advantage of a naturally occurring period of stasis in the arteries…

Thursday, December 01, 2011 | Source: TCT 2011

ROTAXUS: Rotablation Does Not Improve Stenting Results in Calcified Lesions

By Yael L. Maxwell

SAN FRANCISCO, CA—Rotational atherectomy does not increase efficacy of drug eluting stents (DES) in complex calcified lesions compared with standard…

Thursday, December 01, 2011 | Source: TCT 2011

COBRA: Postdilation with Cryoplasty Reduces Restenosis in Diabetic SFA Lesions

By Jason Kahn

SAN FRANCISCO, CA—Using cryoplasty for postdilation following stent implantation reduces restenosis compared with conventional balloon angioplasty…

Tuesday, November 29, 2011 | Source: TCT 2011

TWENTE: Zotarolimus DES Noninferior to Everolimus DES at 1 Year

By L.A. McKeown

SAN FRANCISO, CA—New generation zotarolimus eluting stents are noninferior to everolimus eluting stents at 1 year in patients with stable angina or…

Monday, November 28, 2011 | Source: TCT 2011

PEPCAD-DES: Drug-Coated Balloon Better Than Uncoated Balloon for DES Restenosis

By Kim Dalton

SAN FRANCISCO, CA—For revascularization of restenotic lesions in drug eluting stents (DES), angioplasty with a paclitaxel coated balloon reduces late…

Wednesday, November 23, 2011 | Source: TCT 2011

ACCEL-BLEED: Mild Bleeding Correlated with Platelet Reactivity One Month Post PCI

By TCT Daily Staff

SAN FRANCISCO, CA—In East Asian patients on antiplatelet therapy following percutaneous coronary intervention (PCI), levels of platelet reactivity…

Wednesday, November 23, 2011 | Source: TCT 2011

RIBS III: Alternative DES Best Bet for DES In-Stent Restenosis

By TCT Dailies Staff

SAN FRANCISCO, CA—The best strategy for treating DES in stent restenosis is implantation of a different type of DES, according to results of the prospective,…

Tuesday, November 22, 2011 | Source: TCT 2011

Stent Thrombosis Linked to Uncovered, Malapposed Stent Struts

By TCT Daily Staff

SAN FRANCISCO, CA Patients who develop stent thrombosis after percutaneous coronary intervention are more likely to have uncovered and or malapposed…

Tuesday, November 22, 2011 | Source: TCT 2011

SPICE: Esomeprazole Reduces Antiplatelet Effect of Clopidogrel

By TCT Daily Staff

SAN FRANCISCO, CA—Patients who have undergone percutaneous coronary intervention (PCI) may experience a decreased antiplatelet effect of clopidogrel…

Monday, November 21, 2011 | Source: TCT 2011

Paclitaxel-Eluting Bioabsorbable Stent Shows Advantage over Bare-Metal Version

By Yael Maxwell
SAN FRANCISO, CA—In 6 month results, a new paclitaxel eluting bioabsorbable stent shows a strong safety profile and improved efficacy compared with an…